THE EFFECT OF HYALURONAN ON INTERLEUKIN-1-ALPHA-INDUCED PROSTAGLANDIN-E2 PRODUCTION IN HUMAN OSTEOARTHRITIC SYNOVIAL-CELLS

被引：97
|
作者：
YASUI, T [1 ]
AKATSUKA, M [1 ]
TOBETTO, K [1 ]
HAYAISHI, M [1 ]
ANDO, T [1 ]
机构：
[1] HAYAISHI HOSP,OSAKA,JAPAN
来源：
AGENTS AND ACTIONS | 1992年 / 37卷 / 1-2期
关键词：
D O I：
10.1007/BF01987905
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An in vitro study on the effects of hyaluronan (HA) on interleukin-1alpha-induced prostaglandin E2 (PGE2) production in human osteoarthritic synovial cells indicated that PGE2 induction was suppressed by HA in a dose- and molecular weight-dependent manner.
引用
收藏
页码：155 / 156
页数：2
相关论文
共 50 条
  • [31] CYCLIC ADENOSINE 3'5' MONOPHOSPHATE STIMULATES PROSTAGLANDIN-E PRODUCTION BY HUMAN ADHERENT SYNOVIAL-CELLS
    BAKER, DG
    BAUMGARTEN, DF
    BOMALASKI, JS
    ZURIER, RB
    PROSTAGLANDINS, 1985, 30 (04): : 669 - 682
  • [32] INTERLEUKIN-1 INDUCED PROSTAGLANDIN-E2 SYNTHESIS BY HUMAN DERMAL FIBROBLASTS IN COLLAGEN GELS
    BARR, RM
    SYMONDS, PH
    AKPAN, AS
    GREAVES, MW
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1990, 95 (04) : 461 - 461
  • [33] STIMULATION OF PROSTAGLANDIN-E AND COLLAGENASE RELEASE FROM HUMAN ADHERENT SYNOVIAL-CELLS BY ALPHA-2-MACROGLOBULIN PROTEINASE COMPLEXES
    LINDSLEY, HB
    FEDERATION PROCEEDINGS, 1987, 46 (04) : 1326 - 1326
  • [34] EFFECT OF RETINOIDS ON PROSTAGLANDIN-E2 AND MONONUCLEAR CELL FACTOR (INTERLEUKIN-1-LIKE) PRODUCTION BY HUMAN MONOCYTE CULTURES
    DAYER, JM
    DUDEZ, T
    DERMATOLOGICA, 1984, 169 (04): : 237 - 238
  • [35] BRADYKININ STIMULATES THE PRODUCTION OF PROSTAGLANDIN-E2 AND INTERLEUKIN-6 IN HUMAN OSTEOBLAST-LIKE CELLS
    RAHMAN, S
    BUNNING, RAD
    DOBSON, PRM
    EVANS, DB
    CHAPMAN, K
    JONES, TH
    BROWN, BL
    RUSSELL, RGG
    BIOCHIMICA ET BIOPHYSICA ACTA, 1992, 1135 (01) : 97 - 102
  • [36] EFFECT OF INTERLEUKIN-1 ON FREE ARACHIDONIC-ACID LEVELS IN HUMAN SYNOVIAL-CELLS
    ONEILL, LAJ
    LEWIS, GP
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1988, 16 (03) : 286 - 286
  • [37] EFFECT OF ANTI-RHEUMATIC DRUGS ON INTERLEUKIN-1 ACTIVITY IN HUMAN SYNOVIAL-CELLS
    ONEILL, LAJ
    LEWIS, GP
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1988, 16 (05) : 892 - 892
  • [38] SYNTHESIS OF INTERLEUKIN-1 AND PROSTAGLANDIN-E2 BY LENS EPITHELIAL-CELLS OF HUMAN CATARACTS
    NISHI, O
    NISHI, K
    IMANISHI, M
    BRITISH JOURNAL OF OPHTHALMOLOGY, 1992, 76 (06) : 338 - 341
  • [39] PROSTAGLANDIN-E1, PROSTAGLANDIN-E2, AND PROSTAGLANDIN-F2-ALPHA IN HUMAN-MILK AND PLASMA
    SHIMIZU, T
    YAMASHIRO, Y
    YABUTA, K
    BIOLOGY OF THE NEONATE, 1992, 61 (04): : 222 - 225
  • [40] EFFECTS OF HUMAN MONONUCLEAR CELL FACTOR ON CULTURED RHEUMATOID SYNOVIAL-CELLS - INTERACTIONS OF PROSTAGLANDIN-E2 AND CYCLIC ADENOSINE-3',5'-MONOPHOSPHATE
    DAYER, JM
    GOLDRING, SR
    ROBINSON, DR
    KRANE, SM
    BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 586 (01) : 87 - 105
12345