A MULTICENTER DOUBLE-BLIND TRIAL OF FLUOXETINE VERSUS AMITRIPTYLINE IN THE TREATMENT OF DEPRESSIVE-ILLNESS

被引：21
|
作者：
JUDD, FK
MOORE, K
NORMAN, TR
BURROWS, GD
GUPTA, RK
PARKER, G
机构：
[1] ROYAL CANBERRA HOSP, GARRAN, ACT, AUSTRALIA
[2] UNIV NEW S WALES, PRINCE WALES HOSP, SCH PSYCHIAT, RANDWICK, NSW, AUSTRALIA
来源：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY | 1993年 / 27卷 / 01期
关键词：
D O I：
10.3109/00048679309072123
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The antidepressant efficacy and side effect prof ile of a fixed dose of 20 mg/day of fluoxetine, a specific serotonin reuptake inhibitor, were compared to those of amitriptyline. Fifty-eight patients with DSM-111-R depression were randomly assigned to receive either fluoxetine or amitriptyline. Fifty-six patients (fluoxetine N = 23, amitriptyline N = 23) completed the 6 week study. Comparable antidepressant efficacy was demonstrated for the two drugs. Patients taking fluoxetine reported less side-effects than those taking amitriptyline.
引用
收藏
页码：49 / 55
页数：7
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