SAMPLE-SIZE DETERMINATION FOR PAIR-MATCHED CASE CONTROL STUDIES WHERE THE GOAL IS INTERVAL ESTIMATION OF THE ODDS RATIO

被引：13

作者：

SATTEN, GA

KUPPER, LL

机构：

[1] Department of Biostatistics, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill

来源：

JOURNAL OF CLINICAL EPIDEMIOLOGY | 1990年 / 43卷 / 01期

关键词：

Case-control study; Confidence; interval; Matched pairs; Odds ratio; Sample size;

D O I：

10.1016/0895-4356(90)90056-U

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Sample sizes are calculated for case-control studies where 1:1 matching has been employed, and where the goal is the interval estimation of the odds ratio. The optimal sample size is defined to be the smallest value for which a 100(1 - α)% confidence interval for the log odds ratio will not exceed a specified width 2δ with specified probability (1 - γ). This approach is similar in spirit to the power-based approach for sample size determination when significance testing is the goal. Tables of sample sizes are presented for various choices of parameters. We also find considerable disagreement with a published method based on expected numbers of discordant pairs. © 1990.

引用

页码：55 / 59

页数：5

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