CHANGES IN PLATELET MEMBRANE FLUIDITY OF MIGRAINE PATIENTS

被引：11
|
作者：
COTRIM, MD
RIBEIRO, CAF
DEMACEDO, TDA
机构：
[1] UNIV COIMBRA,FAC MED,INST PHARMACOL & EXPTL THERAPEUT,P-3400 COIMBRA,PORTUGAL
[2] UNIV COIMBRA,FAC MED,DEPT NEUROL,P-3400 COIMBRA,PORTUGAL
来源：
CEPHALALGIA | 1993年 / 13卷 / 02期
关键词：
MEMBRANE FLUIDITY; MIGRAINE; PLATELETS; TMA-DPH;
D O I：
10.1046/j.1468-2982.1993.1302099.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Platelet membrane fluidity was measured in migraine patients, with and without aura, using the fluorescent probe TMA-DPH (1-[4-(trimethylammonium) phenyl]-6-hexa-1,3,5-triene). Polarization values for TMA-DPH were significantly higher in the platelet membranes of migraine patients (with or without aura) than in those of healthy subjects. These findings signify decreased membrane fluidity and may explain some modifications in receptors, carriers or enzymes described in platelets of migraine patients.
引用
收藏
页码：99 / 101
页数：3
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