PARTICLE-SIZE EFFECTS ON THE DEHYDRATION OF DICALCIUM PHOSPHATE DIHYDRATE POWDERS

被引：15
|
作者：
LANDIN, M
ROWE, RC
YORK, P
机构：
[1] UNIV BRADFORD,SCH PHARM,BRADFORD BD7 1DP,W YORKSHIRE,ENGLAND
[2] FAC FARM SANTIAGO DE COMPOSTELA,DEPT FARMACOL FARM & TECNOL FARMACEUT,SANTIAGO,SPAIN
[3] ZENECA,DIV PHARMACEUT,MACCLESFIELD,CHESHIRE,ENGLAND
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1994年 / 104卷 / 03期
关键词：
DICALCIUM PHOSPHATE DIHYDRATE; DEHYDRATION BEHAVIOR; PARTICLE SIZE;
D O I：
10.1016/0378-5173(94)90167-8
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The particle size of dicalcium phosphate dihydrate (DCPD) has a strong influence on its dehydration behaviour, specifically the weight loss in the first stage of dehydration. This weight loss has been found to be inversely proportional to the mean particle size of the samples. Mean particle size may be a useful parameter in predicting the dehydration behaviour of DCPD and is clearly a contributing factor in explaining batch and source variation.
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页码：271 / 275
页数：5
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