EVALUATION OF HTLV-I/II INFECTION IN BLOOD-DONORS IN BUENOS-AIRES

被引：0

作者：

GUTFRAIND, Z ^{[1
]}

BLEJER, JL ^{[1
]}

SAGUIER, MC ^{[1
]}

CARRETERO, MLG ^{[1
]}

PIROLA, DA ^{[1
]}

VESCIO, LAC ^{[1
]}

机构：

[1] FDN FAVALORO, INST CARDIOL & CIRUGIA CARDIOVASC, DIV MED TRANSFUS, RA-1093 BUENOS AIRES, DF, ARGENTINA

来源：

MEDICINA-BUENOS AIRES | 1995年 / 55卷 / 04期

关键词：

HTLV-I II; BLOOD DONORS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

HTLV-I and HTLV-II are two related retroviruses that are transmitted by sexual contact, breast feeding, blood transfusion and needle sharing. In this study the prevalence of HTLV-I and HTLV-II was evaluated in voluntary blood donors as a measure of the infection in the general population. Samples were tested by a gelatine particle agglutination test and repeatedly reactive samples were confirmed by Western blot tests (WBT), enriched with recombinant rgp21, rgp46I y rgp46II proteins, which differentiates HTLV-I acid HTLV-II antibodies. Of 19,426 samples, 40 were repeatedly reactive by particle agglutination (0.21%). When analyzed by WBT, 6 met the criteria for HTLV-I (0.036%), 2 for HTLV-II (0.01%) and 1 for HTLV-I/II, 13 samples were indeterminate and 18 were negative. The prevalence is low and comparable to that from non endemic countries. Screening for anti HTLV-I/II antibodies is necessary to prevent transmission through blood transfusions.

引用

页码：295 / 299

页数：5

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