ABO Incompatible Kidney Transplantation-Current Status and Uncertainties

被引:21
|
作者
Shin, Milljae [1 ]
Kim, Sung-Joo [1 ]
机构
[1] Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Surg,Div Transplant Surg, 50 Ilwon Dong, Seoul 135710, South Korea
关键词
D O I
10.1155/2011/970421
中图分类号
R61 [外科手术学];
学科分类号
摘要
In the past, ABO blood group incompatibility was considered an absolute contraindication for kidney transplantation. Progress in defined desensitization practice and immunologic understanding has allowed increasingly successful ABO incompatible transplantation during recent years. This paper focused on the history, disserted outcomes, desensitization modalities and protocols, posttransplant immunologic surveillance, and antibody-mediated rejection in transplantation with an ABO incompatible kidney allograft. The mechanism underlying accommodation and antibody- mediated injury was also described.
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页数:11
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