Rheumatoid arthritis is an autoimmune disease caused by periodontal pathogens

被引：41

作者：

Ogrendik, Mesut ^{[1
]}

机构：

[1] Nazilli State Hosp, Div Phys Therapy & Rheumatol, Nazilli, Turkey

来源：

INTERNATIONAL JOURNAL OF GENERAL MEDICINE | 2013年 / 6卷

关键词：

etiopathogenesis; chronic arthritis; periodontitis; Porphyromonas gingivalis; systemic disease; animal models; antibiotics;

D O I：

10.2147/IJGM.S45929

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A statistically significant association between periodontal disease (PD) and systemic diseases has been identified. Rheumatoid arthritis (RA), which is a chronic inflammatory joint disease, exhibits similar characteristics and pathogenesis to PD. The association between RA and PD has been investigated, and numerous publications on this subject exist. Approximately 20 bacterial species have been identified as periodontal pathogens, and these organisms are linked to various types of PD. The most analyzed species of periodontopathic bacteria are Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans. Antibodies and DNA from these oral pathogens have been isolated from the sera and synovial fluids of RA patients. This rapid communication describes the role of periodontal pathogens in the etiopathogenesis of RA.

引用

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页码：383 / 386

页数：4

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