A NEW BASTADIN FROM THE SPONGE PSAMMAPLYSILLA-PURPUREA

被引：53
|
作者：
CARNEY, JR
SCHEUER, PJ
KELLYBORGES, M
机构：
[1] UNIV HAWAII MANOA,DEPT CHEM,HONOLULU,HI 96822
[2] HARBOR BRANCH OCEANOG INST INC,FT PIERCE,FL 34936
来源：
JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 01期
关键词：
D O I：
10.1021/np50091a025
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new bastadin 2 and the previously reported bastadins 5 [3], 7 [4], and 12 (formerly bastadin 9) [5] were isolated from the Verongid sponge Psammaplysilla purpurea collected in Pohnpei. ComPound 2 is mildly cytotoxic against several cell lines and inhibits the enzymes topoisomerase II and dehydrofolate reductase.
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收藏
页码：153 / 157
页数：5
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