New bromotyrosine alkaloids from the marine sponge Psammaplysilla purpurea

被引：53
|
作者：
Tilvi, S [1 ]
Rodrigues, C [1 ]
Naik, CG [1 ]
Parameswaran, PS [1 ]
Wahidhulla, S [1 ]
机构：
[1] Natl Inst Oceanog, Panaji, Goa, India
来源：
TETRAHEDRON | 2004年 / 60卷 / 45期
关键词：
antimicrobial activity; bromotyrosine alkaloids; marine sponge; Psammaplysilla purpurea; purpurealidin;
D O I：
10.1016/j.tet.2004.09.009
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Seven new bromotyrosine alkaloids Purpurealidin A, B, C, D, F, G, H and the known compounds Purealidin Q, Purpurealidin E, 16-Debromoaplysamine-4 and Purpuramine I have been isolated from the marine sponge Psammaplysilla purpurea. Their structure was elucidated on the basis of detailed 1D, 2D NMR and MS spectroscopic data. Purpurealidin B, 16-Debromoaplysamine-4 and Purpuramine I exhibited in vitro antimicrobial activities against E. coli, S. aureus, and V. cholerae. In addition, Purpurealidin B and 16-Debromoaplysamine-4 were also active against Shigella flexineri and Salmonella typhi while Purealidin Q was bactericidal only against Salmonella typhi. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：10207 / 10215
页数：9
相关论文
共 50 条
  • [1] JBIR-44, a new bromotyrosine compound from a marine sponge Psammaplysilla purpurea
    Takeshi Fujiwara
    Ji-Hwan Hwang
    Akihiko Kanamoto
    Hiroshi Nagai
    Motoki Takagi
    Kazuo Shin-ya
    [J]. The Journal of Antibiotics, 2009, 62 : 393 - 395
  • [2] JBIR-44, a new bromotyrosine compound from a marine sponge Psammaplysilla purpurea
    Fujiwara, Takeshi
    Hwang, Ji-Hwan
    Kanamoto, Akihiko
    Nagai, Hiroshi
    Takagi, Motoki
    Shin-ya, Kazuo
    [J]. JOURNAL OF ANTIBIOTICS, 2009, 62 (07): : 393 - 395
  • [3] Two new bromotyrosine-derived metabolites from the sponge Psammaplysilla purpurea
    Goud, TV
    Srinivasulu, M
    Reddy, VLN
    Reddy, AV
    Rao, TP
    Kumar, DS
    Murty, US
    Venkateswarlu, Y
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2003, 51 (08) : 990 - 993
  • [4] Purealidins A similar to R, new bromotyrosine alkaloids from an Okinawan marine sponge Psammaplysilla purea
    Kobayashi, J
    Tsuda, M
    Agemi, K
    Honma, K
    Shigemori, H
    Ishibashi, M
    Sasaki, T
    [J]. PEPTIDE CHEMISTRY 1995, 1996, : 197 - 200
  • [5] PURPURAMINES A-I, NEW BROMOTYROSINE-DERIVED METABOLITES FROM THE MARINE SPONGE PSAMMAPLYSILLA-PURPUREA
    YAGI, H
    MATSUNAGA, S
    FUSETANI, N
    [J]. TETRAHEDRON, 1993, 49 (18) : 3749 - 3754
  • [6] Identifying the related compounds using electrospray ionization tandem mass spectrometry: bromotyrosine alkaloids from marine sponge Psammaplysilla purpurea
    Tilvi, Supriya
    D'Souza, Lisette
    [J]. EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2012, 18 (03) : 333 - 343
  • [7] 3 NEW BROMOTYROSINE-DERIVED METABOLITES OF THE SPONGE PSAMMAPLYSILLA-PURPUREA
    JUREK, J
    YOSHIDA, WY
    SCHEUER, PJ
    KELLYBORGES, M
    [J]. JOURNAL OF NATURAL PRODUCTS, 1993, 56 (09): : 1609 - 1612
  • [8] PUREALIDINS E-G, NEW BROMOTYROSINE ALKALOIDS FROM THE OKINAWAN MARINE SPONGE PSAMMAPLYSILLA-PUREA
    TSUDA, M
    SHIGEMORI, H
    ISHIBASHI, M
    KOBAYASHI, J
    [J]. JOURNAL OF NATURAL PRODUCTS, 1992, 55 (09): : 1325 - 1327
  • [9] PUREALIDINS J-R, NEW BROMOTYROSINE ALKALOIDS FROM THE OKINAWAN MARINE SPONGE PSAMMAPLYSILLA-PUREA
    KOBAYASHI, J
    HONMA, K
    SASAKI, T
    TSUDA, M
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 1995, 43 (03) : 403 - 407
  • [10] 2D NMR Studies of Bromotyrosine Alkaloid, Purpurealidin K from Marine Sponge Psammaplysilla purpurea
    Tilvi, Supriya
    Majik, Mahesh S.
    [J]. CHEMISTRYSELECT, 2019, 4 (21): : 6568 - 6571
12345