STRUCTURE OF 5-[1-(DIAMINOMETHYLENEHYDRAZONO)ETHYL]-4-METHYL-2-METHYLTHIOPYRIMIDINE

被引:2
|
作者
COUSSON, A
NECTOUX, F
BACHET, B
KOKEL, B
HUBERTHABART, M
机构
[1] INST CURIE,PHYS & CHIM SECT,CNRS,URA 448,F-75231 PARIS 05,FRANCE
[2] UNIV PARIS 06,MINERAL & CRISTALLOG LAB,CNRS,LA 09,F-75230 PARIS 05,FRANCE
[3] INST CURIE,INSERM,PHYS & CHIM SECT,F-75231 PARIS 05,FRANCE
关键词
D O I
10.1107/S0108270193002367
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The detailed structure of the title compound (5-acetyl-4-methyl-2-methylthiopyrimidine diaminomethylenehydrazone) revealed distinct differences between it and its already published dichloride salt. It is obviously characterized by its diaminomethylenehydrazono chain and the more symmetrical pyrimidine ring. This observation helps in understanding the chemical behavior of the molecule and sheds more light on the possible mechanism of action of antitumor drugs such as mitoguazone.
引用
收藏
页码:1670 / 1673
页数:4
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