ASYMMETRIC CARBOALKOXYALKYLIDENATION WITH A CHIRAL HORNER-WADSWORTH-EMMONS REAGENT

被引：59
|
作者：
DENMARK, SE
RIVERA, I
机构：
[1] Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 23期
关键词：
D O I：
10.1021/jo00102a005
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The asymmetric carboalkoxyalkylidenation of 4-substituted cyclohexanones was effected by the use of chirally modified Horner-Wadsworth-Emmons (HWE) reagents in good yields (78-82%) as well as high levels of enantioselectivity (78-86% ee).
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页码：6887 / 6889
页数：3
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