VITAMIN-D(3) SYNTHETIC STUDIES - ENANTIOSPECIFIC SYNTHESIS OF THE CD RING FRAGMENT

被引：15

作者：

CLASBY, MC ^{[1
]}

CRAIG, D ^{[1
]}

MARSH, A ^{[1
]}

机构：

[1] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,DEPT CHEM,LONDON SW7 2AY,ENGLAND

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1993年 / 32卷 / 10期

关键词：

D O I：

10.1002/anie.199314441

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The activity of highly oxygenated derivatives of vitamin D3 in cancer and psoriasis therapies makes these compounds attractive synthetic goals. Here the vitamin D3 building block 3 was synthesized enantiospecifcally from (+)‐(R)pulegone (1). The intramolecular cycloaddition of 2 is a key step in the reaction. (Figure Presented.) Copyright © 1993 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1444 / 1446

页数：3

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