OBJECTIVES: To investigate whether endometrial thickness on the day of hCG administration is a predictor of intrauterine insemination (IUI) success. MATERIAL AND METHODS: Three hundred and eighty women undergoing IUI cycles are analysed for Endometrial thickness on the day of hCG administration, Endometrial thickness measurement was done on the day of HCG administration. Correlation between endometrial thickness and factors such as age, dominant follicle numbers, stimulation protocols and pregnancy rate were assessed& compared between pregnant and non pregnant patients. A similar comparison was made between ongoing pregnancies and those that resulted in a loss in a University hospital-based infertility center from Dec 2011-Nov 2012. Main Outcome Measure(s): Endometrial thickness versus IUI outcome. RESULTS: In 220 couples, 365 cycles performed. Pregnancy rate was 14.5%. 90% of pregnancies were ongoing. The mean age of females was 28.6 & mean ET was 8.1mm +-1.47. The mean ET in age range 17-25 yrs was 7.4 +/- 1.98 mm and in age range of >40 years was 6.9 +/- 1.7 mm (p=0<001HS). With increasing the number of 16-18 mm follicles pregnancy rate was 16%, 11% & 15.6% with 1,2 & > 3 follicles. No statistically significant correlation was found between the two.