Mineralocorticoid receptor blockade-a novel approach to fight hyperkalaemia in chronic kidney disease

被引：2
|
作者：
Ritz, E. [1 ]
Pitt, B. [2 ]
机构：
[1] Heidelberg Univ, Nierenzentrum, Heidelberg, Germany
[2] Univ Michigan, Med Sch, Internal Med & Cardiovasc Dis, Ann Arbor, MI 48109 USA
来源：
CLINICAL KIDNEY JOURNAL | 2013年 / 6卷 / 05期
关键词：
aldosterone blockade; chronic kidney disease; hyperkalaemia; potassium binder;
D O I：
10.1093/ckj/sft084
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Hyperkalaemia continues to be a major hazard of mineralocorticoid receptor blockade in an effort to retard the progression of chronic kidney disease (CKD). In cardiac patients on mineralocorticoid receptor blockade, RLY-5016 which captures K+ in the colon has been effective in reducing the risk of hyperkalaemia. This compound might be useful in CKD as well.
引用
收藏
页码：464 / 468
页数：5
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