Double-blind comparison of zopiclone and flunitrazepam in elderly insomniacs with special focus on residual effects

被引：13
|
作者：
Dehlin, O
Rubin, B
Rundgren, A
机构：
[1] RHONE POULENC RORER, HELSINGBORG, SWEDEN
[2] VASA UNIV HOSP, GERIATR CLIN, GOTHENBURG, SWEDEN
来源：
CURRENT MEDICAL RESEARCH AND OPINION | 1995年 / 13卷 / 06期
关键词：
zopiclone; flunitrazepam; insomnia; elderly; sleep;
D O I：
10.1185/03007999509110492
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In a double-blind study of 102 patients with a mean age of 79 years, zopiclone was compared to flunitrazepam. The patients rated their sleep in a diary. There was no statistically significant difference between the relatively low dose of 5 mg zopiclone and 1 mg flunitrazepam for eleven out of the twelve variables measuring subjective sleep quality and quantity. There were no differences between the drugs as regards patients' feelings of being rested or alertness.
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页码：317 / 324
页数：8
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