LAMBERT-EATON MYASTHENIC SYNDROME AND POLYNEUROPATHY IN A PATIENT WITH EPIDERMOID CARCINOMA OF THE LUNG

被引：5
|
作者：
COMOLA, M
NEMNI, R
SHER, E
QUATTRINI, A
FARAVELLI, A
COMI, G
CORBO, M
CLEMENTI, F
CANAL, N
机构：
[1] UNIV MILAN,IRCCS H SAN RAFFAELE,DEPT SURG PATHOL,I-20132 MILAN,ITALY
[2] UNIV MILAN,DEPT MED PHARMACOL,CNR,CTR CYTOPHARMACOL,I-20122 MILAN,ITALY
来源：
EUROPEAN NEUROLOGY | 1993年 / 33卷 / 02期
关键词：
MYASTHENIC SYNDROME; PERIPHERAL NEUROPATHY; EPIDERMOID CARCINOMA; CALCIUM CHANNELS; AUTOANTIBODIES;
D O I：
10.1159/000116917
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We describe a patient affected by the Lambert-Eaton myasthenic syndrome, sensory motor axonal neuropathy and epidermoid carcinoma of the lung. Serum autoantibodies to voltage-operated calcium channels were detected. After lobectomy, voltage-operated calcium channel-related structures were demonstrated in the patient's tumor. By immunocytochemistry, the patient's IgG reacted with neural structures and particularly with intermediate filaments. We think that these autoantibodies may be implicated in the pathogenesis of the neurological symptomatology.
引用
收藏
页码：121 / 125
页数：5
相关论文
共 50 条
  • [11] The Lambert-Eaton Myasthenic Syndrome
    Carpentier, AF
    Delattre, JY
    CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2001, 20 (01) : 155 - 158
  • [12] Lambert-eaton myasthenic syndrome
    Maria B. Weimer
    Joaquin Wong
    Current Treatment Options in Neurology, 2009, 11 : 77 - 84
  • [13] The lambert-eaton myasthenic syndrome
    Antoine F. Carpentier
    Jean-Yves Delattre
    Clinical Reviews in Allergy & Immunology, 2001, 20 : 155 - 158
  • [14] Lambert-Eaton myasthenic syndrome
    Seneviratne, U
    de Silva, R
    POSTGRADUATE MEDICAL JOURNAL, 1999, 75 (887) : 516 - 520
  • [15] Lambert-eaton myasthenic syndrome
    Weimer, Maria B.
    Wong, Joaquin
    CURRENT TREATMENT OPTIONS IN NEUROLOGY, 2009, 11 (02) : 77 - 84
  • [16] Lambert-Eaton myasthenic syndrome
    Hernandez, Micaela A.
    Kohler, Alejandro A.
    Marrodan, Mariano
    Lautre, Andrea
    Brand, Patricio
    Nogues, Martin
    Barroso, Fabio
    REVISTA DE NEUROLOGIA, 2021, 73 (03) : 96 - 100
  • [17] Lambert-Eaton myasthenic syndrome
    Mareska, M
    Gutmann, L
    SEMINARS IN NEUROLOGY, 2004, 24 (02) : 149 - 153
  • [18] Poorly differentiated carcinoma of the lung presenting with Lambert-Eaton myasthenic syndrome
    Nair, SG
    Kumar, BS
    Rajan, B
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2000, 23 (01): : 58 - 59
  • [19] TRENDS IN THE ASSOCIATION OF LAMBERT-EATON MYASTHENIC SYNDROME WITH CARCINOMA
    GUTMANN, L
    PHILLIPS, LH
    GUTMANN, L
    NEUROLOGY, 1992, 42 (04) : 848 - 850
  • [20] LAMBERT-EATON MYASTHENIC SYNDROME AND MERKEL CELL CARCINOMA
    Simmons, Daniel B.
    Duginski, Thomas M.
    McClean, Jeffrey C.
    Amato, Anthony A.
    Sladky, John H.
    MUSCLE & NERVE, 2016, 53 (02) : 325 - 326
12345