Purpose - The purpose of this paper is to identify the main factors affecting information and communication technology (ICT) adoption and process redesign within organizations, with the objective of defining a systematization framework and a set of methods and tools useful for students and practitioners. Design/methodology/approach - The review of literature focused on organizational change and ICT-enabled process innovation allows to extract the key issues for building the model and approaches presented. Findings - The effective introduction of change requires addressing aspects placed at strategy, people, process and enablers level. A system view of these components and their relationships is a key to streamline ICT adoption and process redesign. Research limitations/implications - The roadmap is addressed to support only the design or pre-implementation phase of change, with a major intra-organizational perspective. Originality/value - The main asset of this paper is to combine several frameworks into a unique roadmap to support the investigation of human, process, and technology dimensions of organizational change. Besides, a set of methods and tools are proposed to streamline the design of ICT-enabled and process-based change within an organization.