INDUCTION OF ERRORS IN A DELAYED-RESPONSE TASK BY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION OF THE DORSOLATERAL PREFRONTAL CORTEX

被引：112

作者：

PASCUALLEONE, A

HALLETT, M

机构：

[1] NINCDS,HUMAN MOTOR CONTROL SECT,MED NEUROL BRANCH,BETHESDA,MD 20892

[2] UNIV VALENCIA,DEPT FISIOL,NEUROBIOL UNIT,VALENCIA,SPAIN

来源：

NEUROREPORT | 1994年 / 5卷 / 18期

关键词：

REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION; DELAYED RESPONSE TASK; DORSOLATERAL PREFRONTAL CORTEX; MOTOR CORTEX; HUMANS;

D O I：

10.1097/00001756-199412000-00028

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

WE used repetitive transcranial magnetic stimulation to study the function of the dorsolateral frontal cortex in a delayed response task in 10 normal volunteers. Unilateral stimulation of right or left prefrontal cortex during the delay period between instruction and execution cues led to a significantly greater number of response errors than stimulation of motor cortex or in unstimulated trials. Repetitive transcranial stimulation of appropriate intensity and frequency seems to disrupt the function of mnemonic cells in the prefrontal cortex and is useful for the study of the role of the prefrontal cortex in short-term motor memory.

引用

页码：2517 / 2520

页数：4

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