Roles for Transforming Growth Factor-a and Transforming Growth Factor-beta in Colorectal Cancer

被引：0
|
作者：
Coffey, Robert J. [1 ]
Beauchamp, R. Daniel [1 ]
机构：
[1] Vanderbilt Univ, Suite 4140 MRB 3,465 21st Ave South, Nashville, TN 37232 USA
来源：
CURRENT COLORECTAL CANCER REPORTS | 2006年 / 2卷 / 02期
关键词：
D O I：
10.1007/s11888-006-0005-z
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This review cites some of the notable advances in the last several years in our understanding of the roles of transforming growth factor (TGF)-alpha and TGF-beta in neoplasia in general and colorectal cancer in particular. We have chosen to concentrate on advances that have been made in the treatment of colorectal cancer by pharmacologic blockade of the epidermal growth factor receptor axis and new insights into TGF-beta signaling in colorectal cancer.
引用
收藏
页码：72 / 77
页数：6
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