LONG-TERM SEQUELAE OF PELVIS IRRADIATION - HISTOLOGICAL AND MICRORADIOGRAPHICAL STUDY OF A FEMORAL-HEAD

被引：3

作者：

DELAERE, O ^{[1
]}

ORLOFF, S ^{[1
]}

AUTRIQUE, JC ^{[1
]}

NYSSENBEHETS, C ^{[1
]}

DAMBRAIN, R ^{[1
]}

DHEM, A ^{[1
]}

机构：

[1] CATHOLIC UNIV LOUVAIN,UNITE ANAT HUMAINE,TOUR VESALE 5240,AVE E MOUNIER 52,B-1200 BRUSSELS,BELGIUM

来源：

CLINICAL RHEUMATOLOGY | 1991年 / 10卷 / 02期

关键词：

BONE IRRADIATION; BONE NECROSIS; BONE REMODELING;

D O I：

10.1007/BF02207666

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite the lack of radiological signs, a femoral head showed histological and microradiographical features of osteonecrosis, 54 years after massive irradiation of the right hip. Intertrabecular spaces were invaded by connectivo-vascular tissue with focal accumulation of mast cells, and several resorption foci were filled with mononucleated cells. Moreover, all the microradiographs showed peculiar hypercalcified lines, sometimes containing empty osteocytic lacunae, the origin of which is difficult to precise. This study suggests that massive irradiation of weight-bearing epiphyses may be responsible for particularly long-term hypovascularity, osteonecrosis and disturbed bone remodeling.

引用

页码：206 / 210

页数：5

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