COX2 Inhibitory Activity of Abutilon Indicum

被引：0

作者：

Cinthura, C. ^{[1
]}

Thangavelu, Lakshmi ^{[2
]}

Roy, Anitha ^{[2
]}

机构：

[1] Saveetha Inst Tech & Med Sci, Saveetha Dent Coll, Chennai, Tamil Nadu, India

[2] Saveetha Univ, Saveetha Dent Coll, Dept Pharmacol, Chennai, Tamil Nadu, India

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND ALLIED SCIENCES | 2018年 / 7卷 / 04期

关键词：

Ethnomedicinal; Anti-Arthritic; COX2; Inhibition; Medicinal Uses; Prostaglandin;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Objective : The present study aimed to analyse the COX2 inhibitory activity of Abutilon indicum. Background : Prostaglandins are among the major mediators of the body's response to pain and inflammation, and are constituted of essential fatty acids existing in cell membranes. This reaction was catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms- COX-1 and COX-2. Abutilon indicum, commonly known as the Indian mallow, is famous for its therapeutic values, and further study of its COX-2 inhibitory activity is beneficial. Conclusion : Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will also increase its therapeutic value as an anti-inflammatory with added benefits.

引用

页码：104 / 107

页数：4

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