CAFFEINE DELAYS HABITUATION OF THE HUMAN ACOUSTIC STARTLE REFLEX

被引：0

作者：

SCHICATANO, EJ ^{[1
]}

BLUMENTHAL, TD ^{[1
]}

机构：

[1] WAKE FOREST UNIV,DEPT PSYCHOL,WINSTON SALEM,NC 27109

来源：

PSYCHOBIOLOGY | 1994年 / 22卷 / 02期

关键词：

D O I：

暂无

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

The acoustic startle reflex has proved to be an excellent system for studying habituation in mammals. In animal studies, startle habituation has been found to be sensitive to various pharmacological manipulations. The present experiments were designed to determine whether caffeine (4 mg/kg) modified startle habituation in low and high caffeine users. Human eyeblink responses were measured in a startle habituation paradigm in which 30 trials of 85-dB broadband noise stimuli with a duration of 50 msec and a rise time of .1 msec were presented. Caffeine delayed the habituation of startle amplitude in both low and high users and produced significant dishabituation in low users. These findings indicate that caffeine disrupts early sensory filtering.

引用

页码：117 / 122

页数：6

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