Assessing the benefits and risks of tight glycemic control in critically ill children

被引：0
|
作者：
Kandil, Sarah B. [1 ]
Faustino, E. Vincent [1 ]
机构：
[1] Yale Univ, Sch Med, Dept Pediat, Div Pediat Crit Care, New Haven, CT 06510 USA
来源：
PEDIATRIC HEALTH MEDICINE AND THERAPEUTICS | 2014年 / 5卷
基金：
美国国家卫生研究院;
关键词：
hyperglycemia; hypoglycemia; intensive care unit; insulin; glucose;
D O I：
10.2147/PHMT.S50410
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The benefit of intravenous insulin for tight glycemic control (TGC) in critically ill patients is debatable. Initial single center trials on TGC in critically ill adults admitted to the surgical intensive care unit were promising and showed a decrease in mortality with TGC. However, subsequent multicenter trials were unable to replicate these findings, with one trial even showing increased mortality with TGC. In critically ill children, efficacy and safety of TGC is poorly understood. High rates of insulin-induced hypoglycemia with TGC are concerning. Currently, there are no recommendations on the use of TGC for critically ill children. This review summarizes the current literature on TGC in children, focusing on its benefits and risks.
引用
收藏
页码：93 / 98
页数：6
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