BIOLOGICAL RECEPTORS MEDIATE ANTIPROLIFERATIVE ACTION OF ATRIAL-NATRIURETIC-PEPTIDE IN CULTURED MESANGIAL CELLS

被引：29

作者：

HANEDA, M ^{[1
]}

KIKKAWA, R ^{[1
]}

KOYA, D ^{[1
]}

SAKAMOTO, K ^{[1
]}

NAKANISHI, S ^{[1
]}

MATSUDA, Y ^{[1
]}

SHIGETA, Y ^{[1
]}

机构：

[1] KYOWA HAKKO KOGYO CO LTD,TOKYO RES LABS,TOKYO 194,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 192卷 / 02期

关键词：

D O I：

10.1006/bbrc.1993.1463

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanism of anti-proliferative action of atrial natriuretic peptide (ANP) was examined in cultured mesangial cells. HS-142-1, a selective antagonist for ANP biological receptors, inhibited ANP-induced cellular cGMP accumulation and prevented ANP-induced inhibition of both serum-stimulated incorporation of 3H-thymidine and cell proliferation. Des-[Gln18, Ser19, Gly20, Leu21, Gly22]-ANP4-23-NH2 (C-ANP) failed to inhibit 3H- thymidine incorporation. These results indicate that anti-proliferative action of ANP is mediated by the biological receptors in cultured mesangial cells. © 1993 Academic Press, Inc.

引用

页码：642 / 648

页数：7

共 50 条

[21] INSULIN BLUNTS THE NATRIURETIC ACTION OF ATRIAL-NATRIURETIC-PEPTIDE IN HYPERTENSION
ABOUCHACRA, S
BAINES, AD
ZINMAN, B
SKORECKI, KL
LOGAN, AG
HYPERTENSION, 1994, 23 (06) : 1054 - 1058
[22] POLYAMINE REGULATION OF ATRIAL-NATRIURETIC-PEPTIDE IN CULTURED CARDIOCYTES
TIPNIS, UR
HAILE, C
BOOR, PJ
GUTKOWSKA, J
REGULATORY PEPTIDES, 1994, 52 (02) : 75 - 84
[23] ATRIAL NATRIURETIC PEPTIDE AND NITROPRUSSIDE CAUSE RELAXATION OF CULTURED RAT MESANGIAL CELLS
SINGHAL, PC
DECANDIDO, S
SATRIANO, JA
SCHLONDORFF, D
HAYS, RM
AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 257 (01): : C86 - C93
[24] ATRIAL-NATRIURETIC-PEPTIDE
DOYLE, L
BRITISH JOURNAL OF HOSPITAL MEDICINE, 1985, 34 (06) : U378 - U378
[25] ATRIAL-NATRIURETIC-PEPTIDE
MOELLER, H
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 1986, 111 (06) : 226 - 228
[26] ATRIAL-NATRIURETIC-PEPTIDE
不详
LANCET, 1986, 2 (8503): : 371 - 372
[27] MODULATION BY NACL OF ATRIAL-NATRIURETIC-PEPTIDE RECEPTOR LEVELS AND CYCLIC-GMP RESPONSIVENESS TO ATRIAL-NATRIURETIC-PEPTIDE OF CULTURED VASCULAR ENDOTHELIAL-CELLS
KATAFUCHI, T
MIZUNO, T
HAGIWARA, H
ITAKURA, M
ITO, T
HIROSE, S
JOURNAL OF BIOLOGICAL CHEMISTRY, 1992, 267 (11) : 7624 - 7629
[28] ATRIAL-NATRIURETIC-PEPTIDE
MODI, N
MIDGLEY, JP
ARCHIVES OF DISEASE IN CHILDHOOD, 1992, 67 (11) : 1410 - 1411
[29] ATRIAL-NATRIURETIC-PEPTIDE
BLACK, LS
MONROE, WE
LEE, JC
ROBERTSON, JL
COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN, 1994, 16 (06): : 717 - &
[30] ATRIAL-NATRIURETIC-PEPTIDE
OLIVERA, A
NOVOA, JML
REVISTA CLINICA ESPANOLA, 1987, 181 (01): : 32 - 36

← 1 2 3 4 5 →