SYNTHESIS AND ANTIMICROBIOLOGICAL ACTIVITY OF N-ARYL-SUBSTITUTED 2-METHYL-3-CARBETHOXY-5-PYRROLINONE DERIVATIVES

被引：4
|
作者：
LOVREN, F [1 ]
GAON, ID [1 ]
BOBAREVIC, B [1 ]
机构：
[1] FAC MED SARAJEVO, DEPT MED CHEM, YU-71000 SARAJEVO, YUGOSLAVIA
来源：
ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 11期
关键词：
D O I：
10.1002/ardp.19903231104
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
We describe the synthesis of N‐aryl‐2‐methyl‐3‐carbethoxy‐5‐pyrrolinones benzylidene derivatives, their condensation with azomethines and substitution with aniline. The compounds have been tested for antimicrobial and fungicide activity: they have better fungicidal than bactericidal activity. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
引用
收藏
页码：901 / 904
页数：4
相关论文
共 50 条
  • [31] Synthesis and antibacterial activity of 3-substituted 1-(2-methyl-5-nitrophenyl)-5-oxopyrrolidine derivatives
    Benas Balandis
    Kazimieras Anusevičius
    Jūratė Šiugždaitė
    Kristina Kantminienė
    Vytautas Mickevičius
    Research on Chemical Intermediates, 2019, 45 : 5499 - 5517
  • [32] Synthesis and antibacterial activity of 3-substituted 1-(2-methyl-5-nitrophenyl)-5-oxopyrrolidine derivatives
    Balandis, Benas
    Anusevicius, Kazimieras
    Siugzdaite, Jurate
    Kantminiene, Kristina
    Mickevicius, Vytautas
    RESEARCH ON CHEMICAL INTERMEDIATES, 2019, 45 (11) : 5499 - 5517
  • [33] Synthesis and antiviral activity of N-(4'-phenyl-5'-aryl substituted azothiazoly)-4-substituted benzylidene-2-methyl-imidazol-5-ones
    Sah, P
    Garg, SP
    Nautiyal, SR
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 1997, 6 (03) : 229 - 230
  • [34] Synthesis and antimicrobial activity of 2-[(5-substituted aryl-1′-N-substituted aryl aminomethyl) pyrazol-3-yl] benzofurans
    Kumar, R
    Prasad, VVSR
    Mayur, YC
    Kumar, SMS
    Raju, MH
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2006, 15 (03) : 245 - 248
  • [35] STRUCTURE OF 1-ARYL-3-METHYL-5-(2-BENZOTHIAZOLYL)FORMAZANES N-METHYL DERIVATIVES
    FRADKINA, SP
    OLKHOVIKOVA, NB
    POLYAKOVA, IN
    STARIKOVA, ZA
    SHMELEV, LV
    LIPUNOVA, GN
    ELTSOV, AV
    ZHURNAL OBSHCHEI KHIMII, 1991, 61 (08): : 1883 - 1896
  • [36] SYNTHESIS AND ACTIVITY OF SUBSTITUTED 5-ARYL-2-PYRROLIDINONES (DL)
    BOCCHI, V
    GARDINI, GP
    PINZA, M
    FARMACO-EDIZIONE SCIENTIFICA, 1971, 26 (05): : 429 - &
  • [37] I2/NaH2PO2-mediated deoxyamination of cyclic ethers for the synthesis of N-aryl-substituted azacycles
    Lin, Ying
    Li, Dongyang
    Zhang, Jingjing
    Tang, Zhi
    Liu, Long
    Huang, Tianzeng
    Li, Chunya
    Chen, Tieqiao
    NEW JOURNAL OF CHEMISTRY, 2021, 45 (45) : 21011 - 21014
  • [38] Synthesis and Fungicidal Activities of 2-Substituted-4-methyl-5-aryl-2H-1,2,3-triazole Derivatives
    Bo, Rui
    Lei, Sufang
    Li, Sunyong
    Li, Datuan
    Li, Yuanxiang
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 29 (01) : 87 - 92
  • [39] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME PYRROLE DERIVATIVES. 5. 5-ARYL-3-ETHOXYCARBONYL-2-(4-SUBSTITUTED PIPERAZINO)PYRROLE DERIVATIVES
    COCCO, MT
    ONNIS, V
    SCHIVO, ML
    DELOGU, A
    FARMACO, 1992, 47 (11): : 1395 - 1405
  • [40] Synthesis and antibacterial activity of 1β-methyl-2-[5-(N-substituted-2-hydroxy iminoethyl)pyrrolidin-3-ylthio]carbapenem derivatives
    Oh, CH
    Lee, SC
    Cho, JH
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2003, 38 (7-8) : 751 - 758
12345