HLA IN SINGAPORE CHINESE WITH RHEUMATOID-ARTHRITIS

被引：0
|
作者：
BOEY, ML [1 ]
WEE, GB [1 ]
MOHAN, C [1 ]
HOWE, HS [1 ]
CHAN, SH [1 ]
FENG, PH [1 ]
机构：
[1] NATL UNIV SINGAPORE,FAC MED,WHO,CTR IMMUNOL RES & TRAINING,SINGAPORE 0511,SINGAPORE
来源：
JOURNAL OF RHEUMATOLOGY | 1992年 / 19卷 / 10期
关键词：
RHEUMATOID ARTHRITIS; CHINESE; HLA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The HLA-A, B, C, DR and DQ antigens were determined in 50 Singapore Chinese patients with rheumatoid arthritis (RA). There was a significant increase in the prevalence of HLA-Bw46, DRw53 and DQ3 in patients with RA. The linkage disequilibrium between Bw46 and DRw53 explains this association. This major histocompatibility complex association differs from the HLA-DR4 link in Caucasian populations and suggests that RA is an immunogenetically heterogeneous disease.
引用
收藏
页码：1517 / 1519
页数：3
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