STEREOSPECIFIC SYNTHESIS OF (2S,4R)-[5,5,5-H-2(3)]-LEUCINE

被引：44

作者：

AUGUST, RA ^{[1
]}

KHAN, JA ^{[1
]}

MOODY, CM ^{[1
]}

YOUNG, DW ^{[1
]}

机构：

[1] UNIV SUSSEX,SCH CHEM & MOLEC SCI,BRIGHTON BN1 9QJ,E SUSSEX,ENGLAND

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 32期

关键词：

LEUCINE; STEREOSPECIFIC SYNTHESIS; AMINO ACID; ISOTOPIC LABELING; BIOORGANIC;

D O I：

10.1016/S0040-4039(00)61328-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first fully stereospecific synthesis of a sample of the amino acid (2S)-leucine labelled in only one of the diastereotopic methyl groups has been achieved using (2S)-pyroglutamic acid as a chiral template.

引用

页码：4617 / 4620

页数：4

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