THE EFFECT OF ALUMINUM ON THE STROMAL CELLS (INVITRO) ON BONE-MARROW IN RATS

被引：5
|
作者：
ZAMAN, K
MUKHTAR, M
SIDDIQUE, H
MISZTA, H
机构：
[1] DREXEL UNIV,DEPT BIOSCI & BIOTECHNOL,PHILADELPHIA,PA 19104
[2] JAGIELLONIAN UNIV,TOXICOL LAB,PL-31007 KRAKOW,POLAND
[3] WISTAR INST,PHILADELPHIA,PA 19104
来源：
TOXICOLOGY AND INDUSTRIAL HEALTH | 1992年 / 8卷 / 1-2期
关键词：
BONE MARROW; ERYTHROCYTES; HEMOGLOBIN; ALUMINUM; STROMAL CELLS;
D O I：
10.1177/074823379200800109
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The aim of this study was to describe the effects of aluminum on the stromal cells of rat bone marrow using a combination of in vivo exposure and in vitro culture of bone marrow. The toxic effects of aluminum are manifested by a decrease in the erythrocyte count and hemoglobin level in the peripheral blood. Aluminum stimulated an increase in the number of fibroblasts while the macrophage count dropped. The number of adipocytes remained unaffected. An increase in mean corpuscular hemoglobin (MCH) was also found in the peripheral blood of experimental animals.
引用
收藏
页码：103 / 109
页数：7
相关论文
共 50 条
  • [41] RESPONSE OF BONE-MARROW STROMAL CELLS TO ADIPOGENIC ANTAGONISTS
    GIMBLE, JM
    DORHEIM, MA
    CHENG, Q
    PEKALA, P
    ENERBACK, S
    ELLINGSWORTH, L
    KINCADE, PW
    WANG, CS
    MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (11) : 4587 - 4595
  • [42] HEMATOPOIETIC SUPPORTIVE FUNCTIONS OF CLONED HUMAN BONE-MARROW DERIVED STROMAL CELLS-INVITRO
    AIZAWA, S
    YAGUCHI, M
    NAGASU, M
    TOYAMA, K
    HANDA, H
    EXPERIMENTAL HEMATOLOGY, 1992, 20 (06) : 811 - 811
  • [43] REGULATION OF HEMATOPOIESIS BY BONE-MARROW STROMAL CELLS AND THEIR PRODUCTS
    DORSHKIND, K
    ANNUAL REVIEW OF IMMUNOLOGY, 1990, 8 : 111 - 137
  • [44] COLLAGEN-SYNTHESIS BY BONE-MARROW STROMAL CELLS
    FERNANDEZ, M
    MINGUELL, JJ
    ARCHIVOS DE BIOLOGIA Y MEDICINA EXPERIMENTALES, 1984, 17 (02): : R137 - R137
  • [45] CYTOCHEMICAL DETERMINATION AND INVITRO CULTURES OF BONE-MARROW CELLS
    SCHMALZL, F
    KONWALINKA, G
    BOGUSCH, E
    GEISSLER, D
    PESCHEL, C
    WIEDERMANN, C
    BRAUNSTEINER, H
    ONKOLOGIE, 1981, 4 (05): : 287 - 287
  • [46] RESPONSE OF UREMIC BONE-MARROW CELLS TO ERYTHROPOIETIN INVITRO
    URABE, A
    CHIBA, S
    KOSAKA, K
    TAKAKU, F
    SCANDINAVIAN JOURNAL OF HAEMATOLOGY, 1976, 17 (05): : 335 - 340
  • [47] IN VIVO AND INVITRO PROCESSES FOR CULTURE OF BONE-MARROW CELLS
    LAERUM, OD
    RAJEWSKY, MF
    BLUT, 1974, 28 (03): : 204 - 204
  • [48] BONE-MARROW SUPPRESSOR B-CELLS INVITRO
    FUCHS, BB
    KHAITOV, RM
    PETROV, RV
    ATAULLAKHANOV, RI
    SIDOROVICH, IG
    VANKO, LV
    MALAITSEV, VV
    IMMUNOLOGY, 1978, 35 (06) : 997 - 1003
  • [49] GROWTH OF BONE-MARROW CELLS OF THE RF MOUSE INVITRO
    HORLAND, AA
    MCMORROW, L
    EXPERIMENTAL HEMATOLOGY, 1979, 7 : 109 - 109
  • [50] GROWTH OF BONE-MARROW CELLS ON POROUS CERAMICS INVITRO
    UCHIDA, A
    NADE, S
    MCCARTNEY, E
    CHING, W
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1987, 21 (01): : 1 - 10
12345