Preclinical Alzheimer's disease

被引：1
|
作者：
Gil-Gregorio, P. [1 ]
Yubero-Pancorbo, R. [1 ]
机构：
[1] Hosp Clin San Carlos, Dept Geriatr, Memory Unit, Madrid, Spain
来源：
REVIEWS IN CLINICAL GERONTOLOGY | 2014年 / 24卷 / 02期
关键词：
Alzheimer's disease; preclinical stages; amyloidosis; neurodegeneration; cognition;
D O I：
10.1017/S095925981400001X
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Recently, diagnostic criteria for preclinical Alzheimer's disease have been proposed. These describe and define three stages of disease. Stage I is focused on asymptomatic cerebral amyloidosis. Stage II includes evidence of synaptic dysfunction and/or early degeneration. Finally, stage III of the disease is characterized by the beginning of cognitive decline.
引用
收藏
页码：117 / 121
页数：5
相关论文
共 50 条
  • [21] Preclinical diagnosis of Alzheimer's disease with SPECT
    Johnson, KA
    Jones, KJ
    Becker, JA
    Holman, BL
    Satlin, A
    Albert, MS
    NEUROLOGY, 1997, 48 (03) : 24006 - 24006
  • [22] Endpoints in Preclinical Alzheimer's Disease Trials
    Reiman, Eric M.
    Langbaum, Jessica B.
    Tariot, Pierre N.
    JOURNAL OF CLINICAL PSYCHIATRY, 2014, 75 (06) : 661 - 662
  • [23] Preclinical Alzheimer's disease: a valid concept
    Jack, Clifford R., Jr.
    LANCET NEUROLOGY, 2020, 19 (01): : 31 - 31
  • [24] Cognitive deficits in preclinical Alzheimer's disease
    Small, BJ
    Mobly, JL
    Laukka, EJ
    Jones, S
    Bäckman, L
    ACTA NEUROLOGICA SCANDINAVICA, 2003, 107 : 29 - 33
  • [25] Alzheimer's Disease Preclinical Efficacy Database: Improving the Scientific Rigor, Reproducibility, and Predictive Value of Preclinical Research for Alzheimer's Disease
    Chakraborty, Shreaya
    Sharma, Ali
    Martin, Zane
    Yuan, Jean
    Petanceska, Suzana
    Refolo, Lorenzo
    NEUROTHERAPEUTICS, 2022, 19 (04) : 1425 - 1425
  • [26] Preclinical Alzheimer Disease
    Albert, Marilyn S.
    ANNALS OF NEUROLOGY, 2023, 94 : S276 - S277
  • [27] The neuropsychology of normal aging and preclinical Alzheimer's disease
    Caselli, Richard J.
    Locke, Dona E. C.
    Dueck, Amylou C.
    Knopman, David S.
    Woodruff, Bryan K.
    Hoffman-Snyder, Charlene
    Rademakers, Rosa
    Fleisher, Adam S.
    Reiman, Eric M.
    ALZHEIMERS & DEMENTIA, 2014, 10 (01) : 84 - 92
  • [28] Do preclinical Alzheimer's disease criteria work?
    Petersen, Ronald C.
    LANCET NEUROLOGY, 2013, 12 (10): : 933 - 935
  • [29] Rethinking on the concept of biomarkers in preclinical Alzheimer's disease
    Berti, Valentina
    Polito, Cristina
    Lombardi, Gemma
    Ferrari, Camilla
    Sorbi, Sandro
    Pupi, Alberto
    NEUROLOGICAL SCIENCES, 2016, 37 (05) : 663 - 672
  • [30] Learning and retention in preclinical and early Alzheimer's disease
    Grober, E
    Kawas, C
    PSYCHOLOGY AND AGING, 1997, 12 (01) : 183 - 188
12345