DESTRUCTIVE LYMPHADENOPATHY AND T-LYMPHOCYTE ACTIVATION IN ADULT-ONSET STILLS DISEASE

被引：0
|
作者：
KOELLER, M [1 ]
KIENER, H [1 ]
SIMONITSCH, I [1 ]
ARINGER, M [1 ]
STEINER, CW [1 ]
MACHOLD, K [1 ]
GRANINGER, W [1 ]
机构：
[1] UNIV VIENNA,INST CLIN PATHOL,A-1090 VIENNA,AUSTRIA
来源：
BRITISH JOURNAL OF RHEUMATOLOGY | 1995年 / 34卷 / 10期
关键词：
STILLS DISEASE; LYMPHADENOPATHY; LYMPHOCYTE ACTIVATION; FLOW CYTOMETRY;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recurrent arthritis, fever and lymphadenopathy are symptoms of adult onset of Still's disease (AOSD). Differential diagnosis requires the exclusion of infections or malignant lymphomas. We report on a case of AOSD showing destructive lymphadenopathy, immunophenotyping of peripheral blood leucocytes revealed strong activation of T-lymphocytes. Bone marrow biopsy also showed an increase of lymphopoietic cells to 23%. Analysis of peripheral blood lymphocytes (PBL) after remission showed no remaining signs of activation. Analysis of lymphocyte activation by flow cytometry correlated with disease activity.
引用
收藏
页码：984 / 988
页数：5
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