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DESTRUCTIVE LYMPHADENOPATHY AND T-LYMPHOCYTE ACTIVATION IN ADULT-ONSET STILLS DISEASE
被引:0
|作者:
KOELLER, M
[1
]
KIENER, H
[1
]
SIMONITSCH, I
[1
]
ARINGER, M
[1
]
STEINER, CW
[1
]
MACHOLD, K
[1
]
GRANINGER, W
[1
]
机构:
[1] UNIV VIENNA,INST CLIN PATHOL,A-1090 VIENNA,AUSTRIA
来源:
关键词:
STILLS DISEASE;
LYMPHADENOPATHY;
LYMPHOCYTE ACTIVATION;
FLOW CYTOMETRY;
D O I:
暂无
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Recurrent arthritis, fever and lymphadenopathy are symptoms of adult onset of Still's disease (AOSD). Differential diagnosis requires the exclusion of infections or malignant lymphomas. We report on a case of AOSD showing destructive lymphadenopathy, immunophenotyping of peripheral blood leucocytes revealed strong activation of T-lymphocytes. Bone marrow biopsy also showed an increase of lymphopoietic cells to 23%. Analysis of peripheral blood lymphocytes (PBL) after remission showed no remaining signs of activation. Analysis of lymphocyte activation by flow cytometry correlated with disease activity.
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页码:984 / 988
页数:5
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