THE VITEK IMMUNODIAGNOSTIC ASSAY FOR DETECTION OF IMMUNOGLOBULIN-M TOXOPLASMA ANTIBODIES

被引：12
|
作者：
CANDOLFI, E
RAMIREZ, R
HADJU, MP
SHUBERT, C
REMINGTON, JS
机构：
[1] PALO ALTO MED FDN, RES INST, DEPT IMMUNOL & INFECT DIS, PALO ALTO, CA 94301 USA
[2] STANFORD UNIV, SCH MED, DEPT MED, DIV INFECT DIS & GEOG MED, STANFORD, CA 94305 USA
[3] VITEK SYST INC, HAZELWOOD, MO USA
来源：
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 1994年 / 1卷 / 04期
关键词：
D O I：
10.1128/CDLI.1.4.401-405.1994
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We compared the Vitek immunodiagnostic assay for detection of immunoglobulin M (IgM) toxoplasma antibodies (VIDAS TXM) with an IgM enzyme-linked immunosorbent assay (ELISA) which we developed. A total of 407 serum samples from 391 adults were used for this study. We also examined 17 serial serum samples from four women who had seroconverted during gestation. We observed a sensitivity of 99.5%, a specificity of 93%, a positive predictive value of 93.6%, a negative predictive value of 99.5%, and a global agreement of 96%. In each case of seroconversion the VIDAS TXM became positive at the same time as did the IgM ELISA.
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页码：401 / 405
页数：5
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