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Univ Gothenburg, Sahlgrenska Ctr Cardiovasc & Metab Res, Dept Mol & Clin Med, Sahlgrenska Acad, SE-41345 Gothenburg, Sweden Univ Gothenburg, Sahlgrenska Ctr Cardiovasc & Metab Res, Dept Mol & Clin Med, Sahlgrenska Acad, SE-41345 Gothenburg, Sweden