Clinical, radiographic, electromyographic, and pathologic findings in a cat with fibrodysplasia ossificans progressiva are described. The features of five previously reported cases of this feline disorder are also presented. This disorder affects young adult to middle-aged cats of both sexes. Characteristic clinical features include progressive stiffness of gait, with enlargement of proximal limb musculature. Radiography reveals multiple mineralized densities within the affected musculature. The clinical course is rapid, with development of severe disability within 2 weeks to several months. Electromyographic and pathologic findings suggest that this is a disorder of connective tissue, affecting primarily the epimysium, tendons, and fasciae, and results in marked proliferation of fibrovascular connective tissue, with associated chondroid and osseous metaplasia.
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All India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, India
Kumar, Rajiv Ranjan
Dasgupta, Sauvik
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All India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, India
Dasgupta, Sauvik
Suman, Shiv Kumar
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All India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, India
Suman, Shiv Kumar
Kumar, Uma
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All India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Rheumatol, Room 4076,Fourth Floor,Teaching Block, New Delhi 110029, India