THE EFFECT OF AMPHIPHILIC POLYMERS ON GROWTH OF BORDETELLA-PERTUSSIS AND PRODUCTION OF BORDETELLA-PERTUSSIS HEMAGGLUTININS

被引：2
|
作者：
NIKOLAJEWSKI, HE [1 ]
LIEPERT, H [1 ]
NIKOLAJEWSKI, G [1 ]
PFULLER, U [1 ]
SWIDSINSKI, S [1 ]
WETTIG, G [1 ]
机构：
[1] ACAD SCI GDR,ZENT INST PHYS CHEM,O-1199 BERLIN,GERMANY
来源：
BIOLOGICALS | 1990年 / 18卷 / 04期
关键词：
D O I：
10.1016/1045-1056(90)90034-W
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The effect, upon addition to a culture medium of amphiphilic polymers such as partly hydrolysed polyvinyl acetate (PVAc) or partly methylated cellulose (MeCel) on growth and production of haemagglutinins-the filamentous haemagglutinin (FHA) and the pertussis toxin (PT)-has been investigated. As a result, an increase of HA-titer and PT could be achieved. Besides these effects the addition of the amphiphilic polymers stimulated growth of B. pertussis. The above results are comparable to, or even better than, those obtained by addition of Heptakis (2,6-0-dimethyl) β-cyclodextrin (Me-β-CD) or polyvinyul alcohols (PVA) which have already been described as compounds to enhance growth and yield of haemagglutinins. © 1990.
引用
收藏
页码：305 / 308
页数：4
相关论文
共 50 条
  • [1] SPECIFICITY OF EFFECT OF BORDETELLA-PERTUSSIS IN BORDETELLA-PERTUSSIS MODEL OF ATOPY
    TERPSTRA, GK
    TUBERCLE, 1975, 56 (03): : 246 - 246
  • [2] THE EFFECT OF PH ON THE PRODUCTION OF PERTUSSIS TOXIN BY BORDETELLA-PERTUSSIS
    LICARI, P
    WINBERRY, L
    SWARTZ, R
    JOURNAL OF BIOTECHNOLOGY, 1991, 17 (02) : 189 - 193
  • [3] SEPARATION AND PURIFICATION OF THE HEMAGGLUTININS FROM BORDETELLA-PERTUSSIS
    SATO, Y
    COWELL, JL
    SATO, H
    BURSTYN, DG
    MANCLARK, CR
    INFECTION AND IMMUNITY, 1983, 41 (01) : 313 - 320
  • [4] THE GROWTH OF BORDETELLA-PERTUSSIS - A REVIEW
    ROWATT, E
    JOURNAL OF GENERAL MICROBIOLOGY, 1957, 17 (02): : 297 - 326
  • [5] PROTECTION AGAINST INFECTION WITH BORDETELLA-PERTUSSIS BY AN OLIGOPEPTIDE FROM BORDETELLA-PERTUSSIS
    WILHELM, G
    ROMER, C
    ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIE B-UMWELTHYGIENE KRANKENHAUSHYGIENE ARBEITSHYGIENE PRAVENTIVE MEDIZIN, 1978, 166 (2-3): : 264 - 271
  • [6] EFFECT OF BORDETELLA-PERTUSSIS IN BOVINE
    LEWIS, AJ
    EYRE, P
    PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 1972, 4 (01): : 1 - &
  • [7] PRESERVATION OF BORDETELLA-PERTUSSIS
    ANGRA, SS
    SARAN, G
    GUPTA, P
    EXPERIENTIA, 1980, 36 (03): : 306 - 307
  • [8] BORDETELLA-PERTUSSIS BACTERIOPHAGE
    LAPAEVA, IA
    MEBEL, SM
    PEREVERZEV, NA
    SINYASHINA, LN
    ZHURNAL MIKROBIOLOGII EPIDEMIOLOGII I IMMUNOBIOLOGII, 1980, (05): : 85 - +
  • [9] ADHESION OF BORDETELLA-PERTUSSIS
    MERTSALOVA, NU
    BANDMAN, OA
    SHMELEVA, EI
    ZHURNAL MIKROBIOLOGII EPIDEMIOLOGII I IMMUNOBIOLOGII, 1987, (07): : 96 - 102
  • [10] NEUROTOXICITY OF BORDETELLA-PERTUSSIS
    PITTMAN, M
    NEUROTOXICOLOGY, 1986, 7 (01) : 351 - 351
12345