NMR-STUDIES OF 4(3H)-QUINAZOLINONES AND 4(3H)-QUINAZOLINETHIONES

被引：10

作者：

CHAKRABARTY, M ^{[1
]}

BATABYAL, A ^{[1
]}

MORALESRIOS, MS ^{[1
]}

JOSEPHNATHAN, P ^{[1
]}

机构：

[1] INST POLITECN NACL,CTR INVEST & ESTUDIOS AVANZADOS,DEPT QUIM,MEXICO CITY 07000,DF,MEXICO

来源：

MONATSHEFTE FUR CHEMIE | 1995年 / 126卷 / 6-7期

关键词：

4(3H)-QUINAZOLINONES; 4(3H)-QUINAZOLINETHIONES; H-1; NMR; C-13;

D O I：

10.1007/BF00807171

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Unambiguous H-1 and C-13 NMR assignments for 4(3H)-quinazolinones 1-6 and their corresponding 4-thiones 7-12 have been made. This resulted in the revision of the previous assignments for the two benzenoid carbons (C-5 and C-8) of quinazolinones 1,2,4, and 5. Thionation of the nucleophilic amides 1-6 has been found to cause a distinct change in the C-13 chemical shift of particularly C-4, but also of those of C-4a, C-5, and C-8a. One-bond and several long range heteronuclear coupling constants for the compounds have also been measured.

引用

页码：789 / 794

页数：6

共 50 条

[21] SYNTHESIS AND ANTICONVULSANT ACTIVITY OF 3-AMINO-4(3H)-QUINAZOLINONES
KORNET, MJ
VARIA, T
BEAVEN, W
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1983, 20 (06) : 1553 - 1555
[22] 3-ISOXAZOLYL SUBSTITUTED 4(3H)-QUINAZOLINONES OF PHARMACEUTICAL INTEREST
PLESCIA, S
DAIDONE, G
CERAULO, L
BAJARDI, ML
REINA, RA
FARMACO-EDIZIONE SCIENTIFICA, 1984, 39 (02): : 120 - 124
[23] POTENTIAL CNS ACTIVE AGENTS .2. STUDIES OF 4(3H)-QUINAZOLINONES
LAKHAN, R
SINGH, RL
FARMACO-EDIZIONE SCIENTIFICA, 1988, 43 (09): : 745 - 751
[24] Synthesis, crystallographic studies and biological evaluation of some 2-substituted 3-indazolyl-4(3H)-quinazolinones and 3-indazolyl-4(3H)-benzotriazinones
Daidone, G
Plescia, S
Raffa, D
Schillaci, D
Maggio, B
Benetollo, F
Bombieri, G
HETEROCYCLES, 1996, 43 (11) : 2385 - 2396
[25] Synthesis and anticonvulsant evaluation of some novel 4(3H)-quinazolinones
El-Azab, Adel S.
ElTahir, Kamal E. H.
Attia, Sabry M.
MONATSHEFTE FUR CHEMIE, 2011, 142 (08): : 837 - 848
[26] SYNTHESIS OF SOME NEW 4(3H) QUINAZOLINONES AS POTENTIAL FUNGICIDES
CHAURASIA, MR
SHARMA, SK
KUMAR, S
CURRENT SCIENCE, 1981, 50 (19): : 841 - 843
[27] TRANSFORMATION OF 4(3H)-QUINAZOLINONES TO 2,4-QUINAZOLINEDIONES
KIRMANI, MZ
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1979, 18 (04): : 387 - 388
[28] Some reactions of 2-phenyl-4(3H)-quinazolinones
Abdo, MA
Zeid, IF
El-Hiti, GA
Mahmoud, OE
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1999, 38 (07): : 850 - 853
[29] A recyclable CuO-catalyzed synthesis of 4(3H)-quinazolinones
Zhan, Dan
Li, Tianbin
Wei, Haidong
Weng, Wen
Ghandi, Khashayar
Zeng, Qingle
RSC ADVANCES, 2013, 3 (24): : 9325 - 9329
[30] 2-GUANIDINO-4(3H)-QUINAZOLINONES WITH CHEMOTHERAPEUTICAL ACTIVITIES
KREUTZBERGER, A
BALBACH, S
PHARMAZIE, 1993, 48 (01): : 17 - 20

← 1 2 3 4 5 →