EXCRETION OF BETA-N-ACETYLGLUCOSAMINIDASE IN URINE OF TYPE-I AND TYPE-II DIABETICS WITH AND WITHOUT NEPHROPATHY

被引:0
|
作者
WERLE, E
BOSTEDT, A
FIEHN, W
HASSLACHER, C
机构
[1] UNIV KLIN HEIDELBER,MED KLIN & POLIKLIN,ZENT LAB,HEIDELBERG,GERMANY
[2] UNIV KLIN HEIDELBERG,MED KLIN,ENDOKRINOL & STOFFWECHSEL ABT,HEIDELBERG,GERMANY
关键词
BETA-N-ACETYLGLUCOSAMINIDASE (BETA-NAG); DIABETES-MELLITUS; GLOMERULAR AND TUBULOINTERSTITIAL NEPHROPATHY;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The clinical aspects of the excretion of beta-N-acetylglucosaminidase (beta-NAG, EC3.2.1.30) in urine of type I and type 11 diabetics with and without nephropathy are evaluated. Correlation between concentration of albumin and of beta-NAG activity in urine is determined and the circadian rhythm of beta-NAG excretion in urine is examined, the indication of glomerular and tubulointerstitial damage is discussed. Longitudinal studies should demonstrate, whether an increased beta-NAG activity in urine of diabetics with normoalbuminuria is an indicator of nephropathy or a predictor of nephropathy if raised albuminuria is observed.
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页码:59 / 62
页数:4
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