METABOLISM OF INTRAVENOUSLY ADMINISTERED MALTOSE IN RENAL TUBULES IN HUMANS

被引:15
|
作者
TAHARA, Y [1 ]
FUKUDA, M [1 ]
YAMAMOTO, Y [1 ]
NOMA, Y [1 ]
YAMATO, E [1 ]
CHA, T [1 ]
YONEDA, H [1 ]
IKEGAMI, H [1 ]
HIROTA, M [1 ]
SHIMA, K [1 ]
机构
[1] UNIV TOKUSHIMA,SCH MED,DEPT LAB MED,TOKUSHIMA 770,JAPAN
来源
AMERICAN JOURNAL OF CLINICAL NUTRITION | 1990年 / 52卷 / 04期
关键词
Glucose; Maltose; Threshold plasma concentration; Tubular reabsorption; Urinary excretion;
D O I
10.1093/ajcn/52.4.689
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
To investigate how urinary excretion rates (UERs) of maltose and glucose are determined after intravenous maltose infusion, maltose and glucose solutions were infused at various rates and the relationships between UERs of maltose and glucose and their plasma concentrations were examined. Results showed the existence of a threshold plasma maltose concentration for the urinary excretions of maltose and glucose and the existence of a maximum rate of urinary glucose excretion after maltose infusion. Elevation of plasma glucose concentration by simultaneous glucose infusion increased urinary glucose excretion but did not increase urinary maltose excretion; the relationship between plasma total sugar concentration and urinary total sugar excretion was unchanged. Results suggest that maltose administered intravenously is hydrolyzed to glucose by maltase in renal tubules and reabsorbed as glucose competitively with glucose derived from plasma and that the maximum utilization of intravenously infused maltose is determined by the tubular glucose reabsorption capacity.
引用
收藏
页码:689 / 693
页数:5
相关论文
共 50 条