LONG-TERM RESULTS OF I-125 IRRADIATION OF UVEAL MELANOMA

被引:0
|
作者
PACKER, S [1 ]
STOLLER, S [1 ]
LESSER, ML [1 ]
MANDEL, FS [1 ]
FINGER, PT [1 ]
机构
[1] CORNELL UNIV, N SHORE UNIV HOSP, COLL MED, DEPT RES, DIV BIOSTAT, MANHASSET, NY 11030 USA
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R77 [眼科学];
学科分类号
100212 ;
摘要
The authors report on 64 of the first 65 patients treated with iodine 125. The mean follow-up was 64.9 months. After treatment, 29 patients (45.3%) retained visual acuity of 20/100 or better, and 18 patients (28.1%) retained visual acuity within two lines of visual acuity before irradiation. Eleven patients (17.2%) died of metastasis, and 5 patients (7.8%) had local recurrence. Cataract developed in 29 (45.3%) patients; keratitis developed in only 2 (3.1%) patients, and dry eye developed in none. Neovascular glaucoma developed in 7 (10.9%) patients, and 15 (23.4%) patients had radiation retinopathy. Eleven patients (17.2%) required enucleation for either tumor growth or neovascular glaucoma. These results show the increasing number of radiation complications seen with long-term observation and the frequently seen adverse visual outcome.
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页码:767 / 774
页数:8
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