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COMPARATIVE INVITRO ACTIVITIES OF SPARFLOXACIN (CI-978, AT-4140) AND OTHER ANTIMICROBIAL AGENTS AGAINST STAPHYLOCOCCI, ENTEROCOCCI, AND RESPIRATORY-TRACT PATHOGENS
被引:33
|作者:
SIMOR, AE
FULLER, SA
LOW, DE
机构:
[1] Department of Microbiology, Mount Sinai Hospital, University of Toronto, Toronto, Ont.
关键词:
D O I:
10.1128/AAC.34.11.2283
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The in vitro activity of sparfloxacin (CI-978; AT-4140) was compared with those of other antimicrobial agents against isolates of staphylococci, enterococci, and various respiratory tract pathogens. Sparfloxacin was the most active drug tested against staphylococci (MIC for 90% of the strains tested [MIC90], 0.125 μg/ml) and enterococci (MIC90, 1.0 μg/ml). It was also active against Haemophilus influenzae (MIC90, ≤0.06 μg/ml), Moraxella (Branhamella) catarrhalis (MIC90, 0.125 μg/ml), Streptococcus pneumoniae (MIC90, 0.5 μg/ml), and Streptococcus pyogenes (MIC90, 1.0 μg/ml).
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页码:2283 / 2286
页数:4
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