ASSESSMENT OF CYTOTOXIC AND GENOTOXIC POTENTIALS OF OCCUPATIONALLY PESTICIDE EXPOSED POPULATION

Biomonitoring markers are gaining considerable importance in epidemiological and experimental biology studies to achieve both a measurement and an estimation of biologically active/passive exposure to genotoxic pollutants. A wide range of chemical products known to be acutely toxic is currently used in the agricultural sector, including numerous pesticides with different compositions. People working in the chemical industry producing pesticides, people spraying pesticides and people dedicated to floriculture or agricultural works in general are the subject of specific sections. In the present study we analysed the cytotoxic and genotoxic effects of pesticides in workers exposed to pesticides by comparing to normal population. The mean mitotic index was higher in pesticide exposed population with 2.029 compared to 5.1 of control samples. SCE's and Cell proliferation kinetics of pesticide exposed population were also statistically significant with mean of 21.194 and 0.321 compared to mean of control samples 5.243 and.04371 respectively.