THE ASYMMETRIC MICHAEL REACTION INVOLVING CHIRAL IMINES - USE OF ACRYLONITRILE AS ACCEPTOR AND SUBSEQUENT FUNCTIONALIZATION OF THE ADDUCTS

被引：8
|
作者：
DESMAELE, D
ZOUHIRI, F
DANGELO, J
机构：
[1] Laboratoire de Chimie Organique associé au CNRS, Centre d'Etudes Pharmaceutiques, 92296 Châtenay-Malabry
来源：
TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 09期
关键词：
ASYMMETRIC MICHAEL ADDITION; CHIRAL IMINES; WITTIG REACTION; EPOXY-SILANES; TRIAZOLE FORMATION;
D O I：
10.1016/0957-4166(94)80071-5
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Condensation of chiral imines 1 and acrylonitrile led to adduct (R)-6 with an ee greater than or equal to 95 %. This adduct has then been converted into chiral synthons 9, 11, 12 and 17.
引用
收藏
页码：1645 / 1648
页数：4
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