HEPATOCELLULAR-CARCINOMA AND SQUAMOUS-CELL CARCINOMA IN A PATIENT WITH FANCONIS ANEMIA

被引：14

作者：

LINARES, M ^{[1
]}

PASTOR, E ^{[1
]}

GOMEZ, A ^{[1
]}

GRAU, E ^{[1
]}

机构：

[1] HOSP XATIVA LLUIS ALCANYIS,DEPT PATHOL,E-46800 VALENCIA,SPAIN

来源：

ANNALS OF HEMATOLOGY | 1991年 / 63卷 / 01期

关键词：

FANCONIS ANEMIA; ANDROGENS; SQUAMOUS CELL CARCINOMA; LIVER NEOPLASMS;

D O I：

10.1007/BF01714963

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute leukemia, hepatocellular carcinoma, and squamous cell carcinoma have been reported in patients with Fanconi's anemia. We report on a 31-year-old woman whod eveloped squamous cell carcinoma of the esophagus and hepatocellular carcinoma. Jaundice and hepatic tumor developed in 1981, after she had received oxymetholone for 10 years. Liver biopsy revealed peliosis hepatis. Androgenic therapy was stopped and the jaundice resolved. However, the hepatic tumor was observed to be unchanged. The patient died of disseminated squamous cell carcinoma, but no metastatic lesions from hepatocellular carcinoma were detected in the autopsy. The association of Fanconi's anemia and squamous cell carcinoma is reviewed, and the malignant potential of androgen-related hepatic tumors is discussed.

引用

页码：54 / 55

页数：2

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