OSTEOPOROSIS IN SEVERE CONGENITAL NEUTROPENIA TREATED WITH GRANULOCYTE-COLONY-STIMULATING FACTOR

被引：0
|
作者：
BISHOP, NJ
WILLIAMS, DM
COMPSTON, JC
STIRLING, DM
PRENTICE, A
机构：
[1] UNIV CAMBRIDGE,DEPT PEDIAT,CAMBRIDGE,ENGLAND
[2] UNIV CAMBRIDGE,DEPT MED,CAMBRIDGE,ENGLAND
[3] UNIV CAMBRIDGE,MRC,DUNN NUTR UNIT,CAMBRIDGE,ENGLAND
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1995年 / 89卷 / 04期
关键词：
SEVERE CONGENITAL NEUTROPENIA; G-CSF; OSTEOPOROSIS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recombinant human granulocyte colony-stimulating factor (G-CSF) has substantially improved life expectancy for children with severe congenital neutropenia (SCN). Severe osteoporosis, reported in this population, may relate to the disease process, or be a therapeutic side-effect. This report details bone loss, quantitated absorptiometrically and histomorphometrically, in a child with SCN and vertebral collapse, and the positive response to anabolic steroid and bisphosphonate therapy.
引用
收藏
页码：927 / 928
页数：2
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