AMETHOPTERINE (METHOTREXATE)PHOSPHONOGLUTAMIC ANALOGS .2. DIHYDROFOLATE-REDUCTASE INHIBITION

被引：0
|
作者：
STURTZ, G [1 ]
GUILLAMOT, G [1 ]
BOURDEAUX, M [1 ]
CHAUVET, M [1 ]
机构：
[1] UNIV AIX MARSEILLE 2,PHYS PHARMACEUT LAB,F-13385 MARSEILLE 4,FRANCE
来源：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1984年 / 19卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：274 / 276
页数：3
相关论文
共 50 条
  • [31] INHIBITION OF DIHYDROFOLATE-REDUCTASE BY PALMITOYL COENZYME-A
    MITA, M
    YASUMASU, I
    [J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1981, 13 (02): : 229 - 232
  • [32] METHOTREXATE ANALOGS .15. A METHOTREXATE ANALOG DESIGNED FOR ACTIVE-SITE-DIRECTED IRREVERSIBLE INACTIVATION OF DIHYDROFOLATE-REDUCTASE
    ROSOWSKY, A
    WRIGHT, JE
    GINTY, C
    UREN, J
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (08) : 960 - 964
  • [33] INTERACTION OF POLYGLUTAMYL DERIVATIVES OF METHOTREXATE, 10-DEAZAAMINOPTERIN, AND DIHYDROFOLATE WITH DIHYDROFOLATE-REDUCTASE
    KUMAR, P
    KISLIUK, RL
    GAUMONT, Y
    NAIR, MG
    BAUGH, CM
    KAUFMAN, BT
    [J]. CANCER RESEARCH, 1986, 46 (10) : 5020 - 5023
  • [34] STRUCTURE OF DIHYDROFOLATE-REDUCTASE GENES IN METHOTREXATE-RESISTANT MOUSE LINES EXPRESSION OF MOUSE DIHYDROFOLATE-REDUCTASE IN ESCHERICHIA-COLI
    NUNBERG, JH
    KAUFMAN, RJ
    CHANG, ACY
    ERLICH, HA
    COHEN, SN
    SCHIMKE, RT
    [J]. JOURNAL OF SUPRAMOLECULAR STRUCTURE, 1979, : 69 - 69
  • [35] ACTION OF INTERMEDIATE DOSES OF METHOTREXATE ON DIHYDROFOLATE-REDUCTASE IN MALIGNANT DISEASES
    TZORTZATOUSTATHOPOULOU, F
    ZAVITSAPATELI, H
    MOUSATOS, G
    PRODROMOU, N
    KAIRIS, M
    PAPPAS, J
    [J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1987, 4 (01) : 43 - 53
  • [36] A MECHANISM OF RESISTANCE TO METHOTREXATE - NADPH BUT NOT NADH STIMULATION OF METHOTREXATE BINDING TO DIHYDROFOLATE-REDUCTASE
    KAMEN, BA
    WHYTEBAUER, W
    BERTINO, JR
    [J]. BIOCHEMICAL PHARMACOLOGY, 1983, 32 (12) : 1837 - 1841
  • [37] A NEW FLUORESCENT DIHYDROFOLATE-REDUCTASE PROBE FOR STUDIES OF METHOTREXATE RESISTANCE
    ROSOWSKY, A
    WRIGHT, JE
    SHAPIRO, H
    BEARDSLEY, P
    LAZARUS, H
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1982, 257 (23) : 4162 - 4167
  • [38] DETERMINATION OF THE DIHYDROFOLATE-REDUCTASE TRANSCRIPTION UNIT IN METHOTREXATE RESISTANT CELLS
    FRAYNE, EG
    LEYS, EJ
    CROUSE, GF
    KELLEMS, RE
    [J]. JOURNAL OF CELL BIOLOGY, 1983, 97 (05): : A354 - A354
  • [39] EXPRESSION OF A METHOTREXATE RESISTANT DIHYDROFOLATE-REDUCTASE GENE IN TRANSGENIC MICE
    ISOLA, LM
    GORDON, JW
    [J]. DEVELOPMENTAL GENETICS, 1989, 10 (05): : 349 - 355
  • [40] PROTONATED STATE OF METHOTREXATE, TRIMETHOPRIM, AND PYRIMETHAMINE BOUND TO DIHYDROFOLATE-REDUCTASE
    COCCO, L
    ROTH, B
    TEMPLE, C
    MONTGOMERY, JA
    LONDON, RE
    BLAKLEY, RL
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, 226 (02) : 567 - 577
12345