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- [34] Quinone isomers of the WS-5995 antibiotics:: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro ANTI-CANCER DRUGS, 2001, 12 (05) : 401 - 417