Chicken embryo: a useful animal model for drug testing?

被引：0

作者：

Ribeiro, L. N. M. ^{[1
]}

Schlemper, A. E. ^{[2
]}

Da Silva, M., V ^{[3
]}

Fonseca, B. B. ^{[1
,2
]}

机构：

[1] Univ Fed Uberlandia, Inst Biotechnol, Uberlandia, MG, Brazil

[2] Univ Fed Uberlandia, Sch Vet Med, Uberlandia, MG, Brazil

[3] Univ Fed Uberlandia, Cent Anim Facil, Uberlandia, MG, Brazil

来源：

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2022年 / 26卷 / 12期

关键词：

Allantoic fluid; Amniotic fluid; Chicken embryo model; Drug delivery system; Shell membrane; Toxicity; Efficacy;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The use of chicken embryos (CEs) as an in vivo experimental model for different pharmaceutical purposes is not a novelty. However, in recent years, the number of reports employing CE to evaluate several parameters, such as the toxicity and efficacy of drugs and/or nanosystems, has increased. Therefore, this review discusses the relevance of CE for drug testing, emphasizing the inoculation routes and the embryonic stages. The challenges to be overcome, as well as some practical recommendations to allow CE to be more explored as a promising in vivo model in drug analyses, are also highlighted.

引用

页码：4828 / 4839

页数：12

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