REDUCTION OF ISOQUINOLINE AND PYRIDINE-CONTAINING HETEROCYCLES WITH LITHIUM TRIETHYLBOROHYDRIDE (SUPER-HYDRIDE(R))

被引:32
|
作者
BLOUGH, BE [1 ]
CARROLL, FI [1 ]
机构
[1] RES TRIANGLE INST,POB 12194,RES TRIANGLE PK,NC 27709
关键词
D O I
10.1016/S0040-4039(00)79297-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Isoquinolines, quinoline and pyridines are effectively reduced to 1,2,3,4-tetrahydroisoquinolines, 1,2,3,4-tetrahydroquinolines and piperidines respectively with lithium triethylborohydride (Super-Hydride(R)). The mechanism of the reduction was explored by reduction of isoquinoline and pyridine with lithium triethylborodeuteride (Super-Deuteride(R)).
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页码:7239 / 7242
页数:4
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