OPTIMIZATION OF HIGH-AFFINITY AT(1)/AT(2)-BALANCED TRIAZOLINONE ANGIOTENSIN-II ANTAGONISTS

被引：0
|
作者：
ASHTON, WT
CHANG, LL
FLANAGAN, KL
GREENLEE, WJ
CHANG, RSL
LOTTI, VJ
SIEGL, PKS
KIVLIGHN, SD
机构：
[1] MERCK RES LABS,RAHWAY,NJ 07065
[2] MERCK RES LABS,W POINT,PA 19486
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1994年 / 208卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：214 / MEDI
相关论文
共 50 条
  • [41] DIHYDROPYRIMIDINE ANGIOTENSIN-II RECEPTOR ANTAGONISTS
    ATWAL, KS
    AHMED, SZ
    BIRD, JE
    DELANEY, CL
    DICKINSON, KEJ
    FERRARA, FN
    HEDBERG, A
    MILLER, AV
    MORELAND, S
    OREILLY, BC
    SCHAEFFER, TR
    WALDRON, TL
    WELLER, HN
    JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (25) : 4751 - 4763
  • [42] NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS
    TIMMERMANS, PBMWM
    WONG, PC
    CHIU, AT
    HERBLIN, WF
    TRENDS IN PHARMACOLOGICAL SCIENCES, 1991, 12 (02) : 55 - 62
  • [43] POTENT, NONPEPTIDIC ANGIOTENSIN-II ANTAGONISTS
    EDWARDS, MP
    ALLOTT, CP
    BRADBURY, RH
    MAJOR, JS
    MASEK, BB
    OLDHAM, AA
    PEARCE, RJ
    ROBERTS, DA
    RUSSELL, ST
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1992, 203 : 177 - MEDI
  • [44] β-Arrestin 1 and 2 stabilize the angiotensin II type I receptor in distinct high-affinity conformations
    Sanni, S. J.
    Hansen, J. T.
    Bonde, M. M.
    Speerschneider, T.
    Christensen, G. L.
    Munk, S.
    Gammeltoft, S.
    Hansen, J. L.
    BRITISH JOURNAL OF PHARMACOLOGY, 2010, 161 (01) : 150 - 161
  • [45] DIRECT, SIMPLIFIED, AND SENSITIVE ASSAY OF ANGIOTENSIN-II IN PLASMA EXTRACTS PERFORMED WITH A HIGH-AFFINITY MONOCLONAL-ANTIBODY
    SIMON, D
    ROMESTAND, B
    HUANG, HM
    BADOUAILLE, G
    FEHRENTZ, JA
    PAU, B
    MARCHAND, J
    CORVOL, P
    CLINICAL CHEMISTRY, 1992, 38 (10) : 1963 - 1967
  • [46] PHARMACOLOGY OF XR510, A POTENT ORALLY-ACTIVE NONPEPTIDE ANGIOTENSIN-II AT(1) RECEPTOR ANTAGONIST WITH HIGH-AFFINITY FOR THE AT(2) RECEPTOR SUBTYPE
    WONG, PC
    QUAN, ML
    SAYE, JM
    BERNARD, R
    CRAIN, EJ
    MCCALL, DE
    WATSON, CA
    ZASPEL, AM
    SMITH, RD
    WEXLER, RR
    TIMMERMANS, PBMWM
    CHIU, AT
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1995, 26 (03) : 354 - 362
  • [47] HIGH-AFFINITY ANGIOTENSIN-II RECEPTORS IN THE BOVINE OVARY ARE DIFFERENT FROM THOSE PREVIOUSLY IDENTIFIED IN OTHER TISSUES
    MIYAZAKI, H
    KONDOH, M
    OHNISHI, J
    MASUDA, Y
    HIROSE, S
    MURAKAMI, K
    BIOMEDICAL RESEARCH-TOKYO, 1988, 9 (04): : 281 - 285
  • [48] A CONFORMATIONALLY RESTRAINED SERIES OF AT(1)-SELECTIVE ANGIOTENSIN-II ANTAGONISTS
    CARPINO, PA
    SNEDDON, SF
    JARDINE, PD
    MAGNUSAYRITEY, GT
    RAUCH, AL
    BURKARD, MR
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (01) : 93 - 98
  • [49] RADIOIODINATED NONPEPTIDE, ANGIOTENSIN-II AT1 RECEPTOR ANTAGONISTS
    BURNS, HD
    BRENNER, NJ
    GIBSON, RE
    BEAUCHAMP, HT
    CHANG, RS
    FIORAVANTI, C
    NAYLOR, EM
    JOURNAL OF NUCLEAR MEDICINE, 1994, 35 (05) : P246 - P246
  • [50] BALANCED AT(1) AND AT(2) ANGIOTENSIN-II ANTAGONISTS .1. NEW ORALLY-ACTIVE 5-CARBOXYL IMIDAZOLYL BIPHENYL SULFONYLUREAS
    DEPREZ, P
    HECKMANN, B
    CORBIER, A
    VEVERT, JP
    FORTIN, M
    GUILLAUME, J
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (22) : 2605 - 2610
12345